Pfam Domains mapped on to the structure: 2Z4V

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00348	Polyprenyl synthetase	PF00348	PF00348

Conserved Domain Database Superfamily Annotations: 2Z4V

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2Z4V	173833	cd00685	Trans_IPPS_HT -	cl00210
2	2Z4V	206903	cl00210	Isoprenoid_Biosyn_C1	superfamily - -
3	2Z4V	206903	cl00210	Isoprenoid_Biosyn_C1	superfamily - -

Structural Details of PDB entry 2Z4V PDBid Chains Hinge Swapped Domain 2Z4V A,B A:18-20,B:18-20 A:4-17,B:4-17 Swapped-domain interface residues and interactions: Chains Residues A 6, 7, 10, 11, 13, 14, 15, 16, 201, 204, 205, B 6, 7, 10, 11, 13, 14, 15, 16, 201, 204, 205, Non-swapped-domain interface residues and interactions: Chains Residues A 18, 19, 20, 24, 27, 28, 30, 79, 82, 83, 99, 101, 102, 103, 105, 106, 109, 110, 112, 113, 114, 116, 117, 120, 126, 127, 129, 130, 133, 137, 138, 140, 141, 142, 144, 145, 148, 149, 151, 152, 155, 156, 160, 168, 169, 172, 173, 180, 208, 296, 299, 300, 303, 312, 339, B 18, 19, 20, 24, 27, 28, 30, 79, 82, 83, 99, 101, 102, 103, 105, 106, 109, 110, 112, 113, 114, 116, 117, 120, 126, 127, 129, 130, 133, 136, 137, 138, 140, 141, 142, 144, 145, 148, 149, 151, 152, 155, 156, 160, 168, 169, 172, 173, 180, 208, 296, 299, 300, 303, 311, 312,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2Z4V

B:2Z4V

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2Z4V.ali
atm file:	2Z4V.atm
cof file:	2Z4V.cof
hbd file:	2Z4V.hbd
html file:	2Z4V.html
pdb file:	2Z4V.pdb
ps file:	2Z4V.ps
psa file:	2Z4V.psa
rtf file:	2Z4V.rtf
sst file:	2Z4V.sst
tem file:	2Z4V.tem