Pfam Domains mapped on to the structure: 2YX5

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF02700	Phosphoribosylformylglycinamidine (FGAM) synthase	PF02700	PF02700

Conserved Domain Database Superfamily Annotations: 2YX5

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2YX5	207199	cl00789	PurS	superfamily - -

Structural Details of PDB entry 2YX5 PDBid Chains Hinge Swapped Domain 2YX5 A,B A:12-17,B:12-17;A:39-42,B:39-42 A:18-38,B:18-38 Swapped-domain interface residues and interactions: Chains Residues A 18, 22, 25, 26, 29, 31, 33, 34, 35, 36, 37, 38, D 43, 44, 45, 46, 47, 48, Non-swapped-domain interface residues and interactions: Chains Residues A 1, 7, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 58, 61, 62, 65, 66, 67, 83, D 1, 7, 18, 22, 25, 26, 29, 31, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 58, 61, 62, 65, 66, 67,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2YX5

D:2YX5

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2YX5.ali
atm file:	2YX5.atm
cof file:	2YX5.cof
hbd file:	2YX5.hbd
html file:	2YX5.html
pdb file:	2YX5.pdb
ps file:	2YX5.ps
psa file:	2YX5.psa
rtf file:	2YX5.rtf
sst file:	2YX5.sst
tem file:	2YX5.tem