Pfam Domains mapped on to the structure: 2VXK
Conserved Domain Database Superfamily Annotations: 2VXK
Structural Details of PDB entry 2VXK
Structural Details of PDB entry 2VXK
PDBid
Chains
Hinge
Swapped Domain
2VXK
A,B
A:183-184,B:183-184
A:185-190,B:185-190
Swapped-domain interface residues and interactions:
Chains
Residues
A
160 , 161 , 162 , 163 , 164 , 165 , 166 , 179 , 180 , 181 , 182 , 183 , 184 , 185 , 186 , 187 , 188 , 189 , 190 ,
B
160 , 161 , 162 , 163 , 164 , 165 , 166 , 179 , 180 , 181 , 182 , 183 , 184 , 185 , 186 , 187 , 188 , 189 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
66 , 70 , 71 , 72 , 73 , 75 , 79 , 80 , 83 , 86 , 87 , 90 , 92 , 93 , 94 , 96 , 113 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 127 , 129 , 130 , 151 , 155 , 159 , 167 , 168 , 171 , 178 ,
B
66 , 70 , 71 , 72 , 73 , 75 , 79 , 80 , 83 , 86 , 87 , 90 , 92 , 93 , 94 , 96 , 113 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 127 , 129 , 130 , 151 , 155 , 159 , 167 , 168 , 171 , 178 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: