3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 2V0N

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00072 Response regulator receiver domain PF00072 PF00072

2 A PF00072 Response regulator receiver domain PF00072 PF00072

3 A PF00990 GGDEF domain PF00990 PF00990

Conserved Domain Database Superfamily Annotations: 2V0N

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 2V0N 143635 cd01949 GGDEF - cl11967

2 2V0N 212337 cl11967 Nucleotidyl_cyc_III superfamily - -

3 2V0N 29071 cd00156 REC - cl09944

4 2V0N 209106 cl09944 REC superfamily - -

5 2V0N 29071 cd00156 REC - cl09944

6 2V0N 209106 cl09944 REC superfamily - -

7 2V0N 209106 cl09944 REC superfamily - -

Structural Details of PDB entry 2V0N

Structural Details of PDB entry 2V0N

PDBid Chains Hinge Swapped Domain

2V0N A,B A:139-146,B:138-146 A:2-138,B:2-137

Swapped-domain interface residues and interactions:

Chains Residues
A 2, 3, 4, 23, 26, 28, 48, 117, 120, 121, 124, 125, 128, 129, 131, 132, 135, 136, 212, 215, 218, 219, 246, 283,

B 2, 3, 4, 23, 26, 28, 48, 120, 121, 124, 125, 127, 128, 129, 131, 132, 135, 212, 215, 219, 246, 286,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 139, 140, 141, 143, 144, 145, 147, 148, 209, 216, 220, 221, 224, 225, 242, 279, 282, 284, 285, 286, 288, 290, 291, 293, 294, 298, 302, 306, 309, 310, 313, 348, 359, 360, 361, 377, 404, 460,

B 139, 140, 142, 145, 209, 216, 220, 221, 224, 225, 242, 245, 279, 282, 283, 285, 287, 288, 289, 290, 291, 292, 293, 298, 299, 300, 301, 302, 306, 309, 310, 313, 335, 336, 339, 340, 359, 360, 361, 366, 368, 369, 377, 378,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2V0N B:2V0N

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 2V0N.ali
atm file: 2V0N.atm
cof file: 2V0N.cof
hbd file: 2V0N.hbd
html file: 2V0N.html
pdb file: 2V0N.pdb
ps file: 2V0N.ps
psa file: 2V0N.psa
rtf file: 2V0N.rtf
sst file: 2V0N.sst
tem file: 2V0N.tem