Pfam Domains mapped on to the structure: 2SPC

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00435	Spectrin repeat	PF00435	PF00435

Gene Ontology Annotations: 2SPC

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0005515	protein binding	GO:0005515

Conserved Domain Database Superfamily Annotations: 2SPC

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2SPC	29138	SPEC	C	cl02488
2	2SPC	207612	SPEC	superfamily	C -
3	2SPC	207612	SPEC	superfamily	C -

Structural Details of PDB entry 2SPC PDBid Chains Hinge Swapped Domain 2SPC A,B A:71-75,B:71-75 A:76-106,B:76-106 Swapped-domain interface residues and interactions: Chains Residues A 11, 15, 18, 22, 40, 44, 47, 51, 62, 65, 69, 72, 76, 78, 79, 80, 82, 83, 86, 87, 89, 90, 92, 93, 94, 96, 97, 98, 100, 101, 103, 104, 106, B 11, 15, 18, 22, 29, 44, 47, 51, 62, 65, 69, 72, 76, 78, 79, 80, 82, 83, 85, 86, 87, 89, 90, 92, 93, 94, 96, 97, 98, 100, 101, 103, 104, 105, Non-swapped-domain interface residues and interactions: Chains Residues A 1, 4, 7, 8, 12, 19, 21, 25, 29, 32, 43, 48, 50, 54, 55, 58, 61, 73, 75, B 0, 1, 4, 7, 8, 21, 25, 28, 34, 40, 43, 48, 54, 55, 58, 61, 68, 73, 75,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2SPC

B:2SPC

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2SPC.ali
atm file:	2SPC.atm
cof file:	2SPC.cof
hbd file:	2SPC.hbd
html file:	2SPC.html
pdb file:	2SPC.pdb
ps file:	2SPC.ps
psa file:	2SPC.psa
rtf file:	2SPC.rtf
sst file:	2SPC.sst
tem file:	2SPC.tem