3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 2RCY

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF03807 NADP oxidoreductase coenzyme F420-dependent PF03807 PF03807

Conserved Domain Database Superfamily Annotations: 2RCY

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 2RCY 212616 cl09931 NADB_Rossmann superfamily - -

2 2RCY 212616 cl09931 NADB_Rossmann superfamily - -

Structural Details of PDB entry 2RCY

Structural Details of PDB entry 2RCY

PDBid Chains Hinge Swapped Domain

2RCY A,E A:248-255,E:248-255 A:256-262,E:256-262

Swapped-domain interface residues and interactions:

Chains Residues
A 229, 232, 256, 257, 262,

E 229, 256, 257,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 14, 67, 68, 92, 115, 116, 117, 120, 122, 124, 126, 150, 152, 154, 158, 161, 162, 163, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 186, 187, 188, 189, 193, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 209, 210, 211, 216, 217, 219, 220, 222, 223, 225, 226, 227, 228, 230, 233, 234, 236, 237, 238, 240, 242, 243, 244, 245, 246, 248, 249, 250, 251, 252, 253, 254,

E 14, 67, 68, 92, 115, 116, 117, 120, 122, 123, 124, 126, 150, 152, 154, 158, 161, 162, 163, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 178, 179, 180, 181, 182, 183, 184, 186, 187, 188, 189, 193, 195, 196, 197, 198, 199, 200, 201, 202, 203, 204, 205, 206, 207, 209, 210, 211, 216, 217, 219, 220, 222, 223, 225, 226, 227, 228, 230, 232, 233, 234, 236, 237, 238, 240, 242, 243, 245, 246, 248, 249, 250, 251, 252, 253, 254,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

E No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2RCY E:2RCY

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 2RCY.ali
atm file: 2RCY.atm
cof file: 2RCY.cof
hbd file: 2RCY.hbd
html file: 2RCY.html
pdb file: 2RCY.pdb
ps file: 2RCY.ps
psa file: 2RCY.psa
rtf file: 2RCY.rtf
sst file: 2RCY.sst
tem file: 2RCY.tem