Pfam Domains mapped on to the structure: 2RBL
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00041
Fibronectin type III domain
PF00041
PF00041
Gene Ontology Annotations: 2RBL
Conserved Domain Database Superfamily Annotations: 2RBL
Structural Details of PDB entry 2RBL
Structural Details of PDB entry 2RBL
PDBid
Chains
Hinge
Swapped Domain
2RBL
A,C,B
A:825-830,C:825-830,B:825-830
A:803-824,C:803-824,B:803-824
Swapped-domain interface residues and interactions:
Chains
Residues
A
803 , 805 , 806 , 809 , 811 , 814 , 815 , 816 , 817 , 818 , 819 , 820 , 821 , 822 , 823 , 824 , 856 , 857 , 858 , 859 , 860 , 861 , 862 , 863 , 865 , 873 , 875 , 881 , 882 , 883 , 885 , 891 ,
B
803 , 804 , 805 , 806 , 809 , 811 , 814 , 815 , 816 , 817 , 818 , 819 , 820 , 821 , 822 , 823 , 824 , 856 , 857 , 858 , 859 , 860 , 861 , 862 , 863 , 865 , 873 , 875 , 880 , 881 , 882 , 883 , 885 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
825 , 829 , 830 , 831 , 833 , 835 , 852 , 853 , 854 , 871 , 877 , 880 , 887 , 889 , 890 ,
B
825 , 829 , 831 , 833 , 835 , 852 , 853 , 854 , 871 , 877 , 887 , 889 , 890 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A MET(825)LYS, GLN(826)PRO, SER(828)ALA, GLN(829)GLU, LEU(830)ILE, SER(824)PHE, MET(825)LYS, GLN(829)GLU, LEU(830)ILE, GLU(831)ASP, SER(824)PHE,
C No mutation No mutation No mutation No mutation
B MET(825)LYS, GLN(826)PRO, SER(828)ALA, GLN(829)GLU, LEU(830)ILE, SER(824)PHE, MET(825)LYS, GLN(829)GLU, GLU(831)ASP, SER(824)PHE,
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: