Pfam Domains mapped on to the structure: 2R28

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00036	EF hand	PF00036	PF00036
2	A	PF00036	EF hand	PF00036	PF00036
3	A	PF00036	EF hand	PF00036	PF00036
4	A	PF00036	EF hand	PF00036	PF00036
5	A	PF13499	EF-hand domain pair	PF13499	PF13499
6	A	PF13499	EF-hand domain pair	PF13499	PF13499
7	A	PF13833	EF-hand domain pair	PF13833	PF13833
8	A	PF13833	EF-hand domain pair	PF13833	PF13833
9	A	PF13833	EF-hand domain pair	PF13833	PF13833
10	A	PF08726	Ca2+ insensitive EF hand	PF08726	PF08726
11	A	PF12763	Cytoskeletal-regulatory complex EF hand	PF12763	PF12763

Structural Details of PDB entry 2R28 PDBid Chains Hinge Swapped Domain 2R28 A,B A:78-82,B:78-82 A:83-148,B:83-148 Swapped-domain interface residues and interactions: Chains Residues A 19, 39, 40, 84, 91, 92, 95, 109, 112, 113, 114, 148, B 19, 22, 39, 40, 41, 84, 91, 92, 95, 112, 113, 114, Non-swapped-domain interface residues and interactions: Chains Residues A 22, 35, 36, 41, B 35,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2R28

B:2R28

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2R28.ali
atm file:	2R28.atm
cof file:	2R28.cof
hbd file:	2R28.hbd
html file:	2R28.html
pdb file:	2R28.pdb
ps file:	2R28.ps
psa file:	2R28.psa
rtf file:	2R28.rtf
sst file:	2R28.sst
tem file:	2R28.tem