Pfam Domains mapped on to the structure: 2R1I
Conserved Domain Database Superfamily Annotations: 2R1I
Structural Details of PDB entry 2R1I
Structural Details of PDB entry 2R1I
PDBid
Chains
Hinge
Swapped Domain
2R1I
A,B
A:154-159,B:154-159
A:160-171,B:160-171
Swapped-domain interface residues and interactions:
Chains
Residues
A
131 , 132 , 133 , 134 , 135 , 136 , 137 , 138 , 139 , 140 , 152 , 153 , 154 , 160 , 161 , 162 , 163 , 165 , 166 , 167 , 168 , 169 , 170 , 171 ,
B
126 , 131 , 132 , 133 , 134 , 135 , 136 , 137 , 139 , 140 , 152 , 153 , 154 , 160 , 161 , 162 , 163 , 165 , 166 , 167 , 168 , 169 , 170 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
39 , 43 , 51 , 56 , 59 , 60 , 63 , 68 , 69 , 83 , 85 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 98 , 100 , 101 , 122 , 126 , 145 , 151 , 155 , 157 , 158 ,
B
39 , 43 , 51 , 56 , 59 , 60 , 63 , 68 , 69 , 83 , 85 , 87 , 88 , 89 , 90 , 91 , 92 , 93 , 98 , 100 , 101 , 122 , 138 , 145 , 151 , 155 , 157 , 158 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: