Pfam Domains mapped on to the structure: 2QSC

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	L	PF13927	Immunoglobulin domain	PF13927	PF13927
2	L	PF13927	Immunoglobulin domain	PF13927	PF13927
3	L	PF00047	Immunoglobulin domain	PF00047	PF00047
4	H	PF13927	Immunoglobulin domain	PF13927	PF13927

Structural Details of PDB entry 2QSC PDBid Chains Hinge Swapped Domain 2QSC H,L H:42-46,L:41-45 H:1-41,L:1-40 Swapped-domain interface residues and interactions: Chains Residues H 35, 39, L 32, 34, 36, 38, Non-swapped-domain interface residues and interactions: Chains Residues H 44, 45, 47, 50, 58, 91, 98, 100, 101, 103, 104, 105, 122, 123, 124, 125, 126, 127, 137, 139, 143, 145, 172, 173, 174, 175, 177, 178, 179, 188, 190, 192, 221, L 41, 42, 43, 44, 46, 49, 50, 55, 87, 89, 91, 94, 95, 96, 98, 99, 100, 116, 118, 119, 121, 123, 124, 127, 129, 131, 133, 135, 137, 138, 160, 161, 162, 163, 164, 167, 174, 176, 178, 180, 214,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
H	No mutation	No mutation	No mutation	No mutation
L	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:2QSC

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2QSC.ali
atm file:	2QSC.atm
cof file:	2QSC.cof
hbd file:	2QSC.hbd
html file:	2QSC.html
pdb file:	2QSC.pdb
ps file:	2QSC.ps
psa file:	2QSC.psa
rtf file:	2QSC.rtf
sst file:	2QSC.sst
tem file:	2QSC.tem