3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 2QNF

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF02945 Recombination endonuclease VII PF02945 PF02945

Conserved Domain Database Superfamily Annotations: 2QNF

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 2QNF 202480 cl03794 Endonuclease_7 superfamily - -

2 2QNF 149982 cl07663 Endonuc-dimeris superfamily - -

3 2QNF 149982 cl07663 Endonuc-dimeris superfamily - -

Structural Details of PDB entry 2QNF

Structural Details of PDB entry 2QNF

PDBid Chains Hinge Swapped Domain

2QNF A,B A:102-107,B:102-107 A:108-157,B:108-157

Swapped-domain interface residues and interactions:

Chains Residues
A 1, 2, 43, 45, 51, 108, 109, 111, 112, 115, 153, 156, 157,

B 1, 2, 43, 45, 51, 108, 109, 111, 112, 115, 153, 156,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 3, 4, 8, 11, 15, 24, 25, 26, 27, 28, 39, 41, 42, 46, 48, 49, 50, 52, 53, 54, 57, 60, 61, 64, 65, 67, 68, 71, 75, 76, 77, 80, 82, 84, 85, 87, 88, 89, 90, 91, 92, 94, 95, 96, 99, 100, 102, 103, 104, 105, 106, 107,

B 3, 4, 8, 11, 15, 24, 25, 26, 27, 28, 41, 46, 48, 49, 50, 52, 53, 54, 57, 60, 61, 64, 65, 67, 68, 71, 75, 76, 77, 80, 82, 84, 85, 87, 88, 89, 90, 91, 92, 94, 95, 96, 99, 100, 102, 103, 104, 105, 106, 107,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation ASN(43)HIS, No mutation No mutation

B No mutation ASN(43)HIS, No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2QNF B:2QNF

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 2QNF.ali
atm file: 2QNF.atm
cof file: 2QNF.cof
hbd file: 2QNF.hbd
html file: 2QNF.html
pdb file: 2QNF.pdb
ps file: 2QNF.ps
psa file: 2QNF.psa
rtf file: 2QNF.rtf
sst file: 2QNF.sst
tem file: 2QNF.tem