3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 2QMX

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00800 Prephenate dehydratase PF00800 PF00800

2 A PF01842 ACT domain PF01842 PF01842

Gene Ontology Annotations: 2QMX

No. GO ID GO Description Linkout - AmiGO

1 GO:0009094 L-phenylalanine biosynthetic process GO:0009094

Conserved Domain Database Superfamily Annotations: 2QMX

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 2QMX 153177 cd04905 ACT_CM-PDT - cl09141

2 2QMX 208988 cl09141 ACT superfamily - -

3 2QMX 144409 cl02968 PDT superfamily - -

4 2QMX 144409 cl02968 PDT superfamily - -

Structural Details of PDB entry 2QMX

Structural Details of PDB entry 2QMX

PDBid Chains Hinge Swapped Domain

2QMX A,B A:54-67,B:54-67 A:3-53,B:3-53

Swapped-domain interface residues and interactions:

Chains Residues
A 30, 31,

B 30, 31,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 54, 55, 56, 57, 58, 59, 60, 61, 102, 103, 104, 106, 107, 110, 121, 123, 124, 125, 166, 168, 206, 208, 209, 211, 212, 215, 216, 219, 220, 222, 224, 225, 226, 227, 228, 229, 230, 231, 232, 234, 240, 280,

B 54, 55, 56, 57, 58, 59, 60, 61, 102, 103, 106, 107, 110, 121, 123, 124, 125, 166, 167, 168, 206, 208, 209, 211, 212, 215, 216, 219, 220, 222, 224, 225, 226, 227, 228, 229, 230, 232, 234, 240,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2QMX B:2QMX

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 2QMX.ali
atm file: 2QMX.atm
cof file: 2QMX.cof
hbd file: 2QMX.hbd
html file: 2QMX.html
pdb file: 2QMX.pdb
ps file: 2QMX.ps
psa file: 2QMX.psa
rtf file: 2QMX.rtf
sst file: 2QMX.sst
tem file: 2QMX.tem