Pfam Domains mapped on to the structure: 2QM8
Conserved Domain Database Superfamily Annotations: 2QM8
Structural Details of PDB entry 2QM8
Structural Details of PDB entry 2QM8
PDBid
Chains
Hinge
Swapped Domain
2QM8
A,B
A:293-297,B:293-297
A:298-329,B:298-329
Swapped-domain interface residues and interactions:
Chains
Residues
A
42 , 46 , 49 , 273 , 276 , 277 , 279 , 281 , 283 , 284 , 302 , 306 , 309 , 310 , 312 , 313 , 314 , 315 , 316 , 317 , 318 , 320 , 321 , 323 , 324 , 327 , 329 ,
B
42 , 46 , 49 , 273 , 276 , 277 , 281 , 283 , 284 , 302 , 306 , 309 , 310 , 312 , 314 , 315 , 316 , 317 , 318 , 320 , 321 , 323 , 324 , 327 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
45 , 138 , 141 , 187 , 189 , 190 , 192 , 193 , 194 , 218 , 219 , 221 , 222 , 224 , 225 , 226 , 227 , 229 , 285 , 287 , 288 , 289 , 292 ,
B
138 , 141 , 181 , 184 , 186 , 187 , 188 , 189 , 190 , 192 , 193 , 195 , 218 , 222 , 225 , 226 , 228 , 285 , 287 , 288 , 289 , 291 , 292 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation PHE(192)LEU, HIS(224)ARG, No mutation
B No mutation No mutation PHE(192)LEU, No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: