Pfam Domains mapped on to the structure: 2QGS

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF01966	HD domain	PF01966	PF01966

Gene Ontology Annotations: 2QGS

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0046872	metal ion binding	GO:0046872

Conserved Domain Database Superfamily Annotations: 2QGS

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2QGS	212171	cl00076	HDc	superfamily - -

Structural Details of PDB entry 2QGS PDBid Chains Hinge Swapped Domain 2QGS A,B A:126-128,B:126-128;A:148-150,B:148-150 A:129-147,B:129-147 Swapped-domain interface residues and interactions: Chains Residues A 23, 25, 130, 131, 133, 134, 137, 138, 141, 142, 144, 146, 204, 207, 208, B 23, 25, 130, 131, 133, 134, 137, 138, 141, 142, 144, 145, 146, 204, 207, 208, 211, Non-swapped-domain interface residues and interactions: Chains Residues A 22, 28, 31, 32, 35, 36, 38, 39, 193, 197, 200, 211, 212, 214, 215, 216, B 28, 32, 35, 36, 38, 39, 193, 196, 197, 200, 212, 214, 215, 216,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

B:2QGS

A:2QGS

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2QGS.ali
atm file:	2QGS.atm
cof file:	2QGS.cof
hbd file:	2QGS.hbd
html file:	2QGS.html
pdb file:	2QGS.pdb
ps file:	2QGS.ps
psa file:	2QGS.psa
rtf file:	2QGS.rtf
sst file:	2QGS.sst
tem file:	2QGS.tem