Pfam Domains mapped on to the structure: 2Q4H
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF01087
Galactose-1-phosphate uridyl transferase, N-terminal domain
PF01087
PF01087
2
A
PF02744
Galactose-1-phosphate uridyl transferase, C-terminal domain
PF02744
PF02744
Conserved Domain Database Superfamily Annotations: 2Q4H
Structural Details of PDB entry 2Q4H
Structural Details of PDB entry 2Q4H
PDBid Chains Hinge Swapped Domain
2Q4H
A,B
A:319-321,B:319-321;A:335-336,B:335-336
A:322-334,B:322-334
Swapped-domain interface residues and interactions:
Chains Residues
A
169 , 171 , 173 , 178 , 179 , 196 , 197 , 198 , 291 , 293 , 295 , 322 , 323 , 324 , 325 , 327 , 328 , 329 , 330 , 331 , 333 ,
B
171 , 173 , 178 , 179 , 196 , 197 , 198 , 291 , 293 , 322 , 323 , 324 , 325 , 327 , 328 , 329 , 330 , 331 , 333 ,
Non-swapped-domain interface residues and interactions:
Chains Residues
A
23 , 24 , 25 , 27 , 29 , 33 , 34 , 36 , 38 , 98 , 99 , 100 , 103 , 116 , 117 , 118 , 119 , 120 , 177 , 190 , 192 , 193 , 194 , 209 , 224 , 240 , 244 , 316 , 351 ,
B
22 , 23 , 24 , 25 , 27 , 33 , 34 , 36 , 38 , 98 , 99 , 100 , 103 , 116 , 117 , 118 , 120 , 169 , 190 , 192 , 194 , 224 , 240 , 244 , 316 ,
Mutations in critical regions:
Chains
Hinge
Domain swapped interface Non-swapped interface Swapped Domain
A No mutation No mutation No mutation No mutation B No mutation No mutation No mutation No mutation B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output:
