Pfam Domains mapped on to the structure: 2PY4
Conserved Domain Database Superfamily Annotations: 2PY4
Structural Details of PDB entry 2PY4
Structural Details of PDB entry 2PY4
PDBid
Chains
Hinge
Swapped Domain
2PY4
A,B
A:119-122,B:119-122
A:123-154,B:123-154
Swapped-domain interface residues and interactions:
Chains
Residues
A
20 , 21 , 22 , 65 , 66 , 67 , 70 , 109 , 110 , 123 , 124 , 125 , 126 , 127 , 128 , 129 , 130 , 133 , 135 , 138 , 139 , 140 , 141 , 142 , 143 , 144 , 145 , 146 , 147 , 148 , 149 , 150 , 151 , 152 , 153 , 154 ,
B
2 , 3 , 4 , 5 , 6 , 7 , 8 , 85 , 86 , 87 , 88 , 123 , 124 , 125 , 126 , 127 , 128 , 129 , 130 , 133 , 135 , 138 , 139 , 140 , 141 , 142 , 143 , 144 , 145 , 146 , 147 , 148 , 149 , 150 , 151 , 152 , 153 , 154 ,
C
2 , 3 , 4 , 5 , 6 , 7 , 8 , 20 , 21 , 22 , 65 , 66 , 67 , 70 , 85 , 86 , 87 , 88 , 109 , 110 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
2 , 3 , 4 , 5 , 6 , 7 , 8 , 9 , 16 , 17 , 19 , 23 , 24 , 25 , 27 , 40 , 41 , 42 , 44 , 50 , 52 , 55 , 57 , 58 , 60 , 62 , 63 , 64 , 68 , 69 , 71 , 72 , 74 , 76 , 77 , 78 , 79 , 81 , 83 , 84 , 85 , 86 , 87 , 88 , 91 , 93 , 95 , 97 , 98 , 99 , 104 , 106 , 113 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 ,
B
9 , 16 , 17 , 19 , 20 , 21 , 22 , 23 , 24 , 25 , 27 , 40 , 41 , 42 , 44 , 50 , 52 , 55 , 57 , 58 , 60 , 62 , 63 , 64 , 65 , 66 , 67 , 68 , 69 , 70 , 71 , 72 , 74 , 76 , 77 , 78 , 79 , 81 , 83 , 84 , 91 , 93 , 95 , 97 , 98 , 99 , 104 , 106 , 109 , 110 , 113 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 ,
C
9 , 16 , 17 , 19 , 23 , 24 , 25 , 27 , 40 , 41 , 42 , 44 , 50 , 52 , 55 , 57 , 58 , 60 , 62 , 63 , 64 , 68 , 69 , 71 , 72 , 74 , 76 , 77 , 78 , 79 , 81 , 83 , 84 , 91 , 93 , 95 , 97 , 98 , 99 , 104 , 106 , 113 , 115 , 116 , 117 , 118 , 119 , 120 , 121 , 122 , 123 , 124 , 125 , 126 , 127 , 128 , 129 , 130 , 133 , 135 , 138 , 139 , 140 , 141 , 142 , 143 , 144 , 145 , 146 , 147 , 148 , 149 , 150 , 151 , 152 , 153 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: