Pfam Domains mapped on to the structure: 2PQM

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00291	Pyridoxal-phosphate dependent enzyme	PF00291	PF00291

Conserved Domain Database Superfamily Annotations: 2PQM

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2PQM	107204	cd01561	CBS_like -	cl00342
2	2PQM	212605	cl00342	Trp-synth-beta_II	superfamily - -
3	2PQM	212605	cl00342	Trp-synth-beta_II	superfamily - -

Structural Details of PDB entry 2PQM PDBid Chains Hinge Swapped Domain 2PQM A,B A:-,B:- A:2--1,B:3--1 Swapped-domain interface residues and interactions: Chains Residues Non-swapped-domain interface residues and interactions: Chains Residues A 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 25, 26, 27, 28, 30, 43, 45, 50, 51, 53, 54, 55, 63, 67, 98, 99, 100, 115, 118, 119, 121, 122, 123, 124, 171, 174, 175, 178, 179, 270, 271, 273, 274, 275, 276, 309, 311, 312, 314, 319, 320, 322, 339, B 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 25, 26, 27, 28, 30, 43, 45, 50, 51, 53, 54, 55, 63, 67, 98, 99, 115, 118, 119, 121, 122, 123, 124, 171, 175, 178, 179, 180, 270, 271, 273, 274, 275, 276, 309, 311, 312, 314, 319, 320, 322,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2PQM

B:2PQM

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2PQM.ali
atm file:	2PQM.atm
cof file:	2PQM.cof
hbd file:	2PQM.hbd
html file:	2PQM.html
pdb file:	2PQM.pdb
ps file:	2PQM.ps
psa file:	2PQM.psa
rtf file:	2PQM.rtf
sst file:	2PQM.sst
tem file:	2PQM.tem