Pfam Domains mapped on to the structure: 2PN8
Conserved Domain Database Superfamily Annotations: 2PN8
Structural Details of PDB entry 2PN8
Structural Details of PDB entry 2PN8
PDBid
Chains
Hinge
Swapped Domain
2PN8
A,B
A:220-232,B:220-232
A:233-269,B:233-269
Swapped-domain interface residues and interactions:
Chains
Residues
A
122 , 123 , 126 , 130 , 164 , 165 , 167 , 220 , 221 , 222 , 223 , 224 , 234 , 235 , 238 , 244 , 245 , 246 , 247 , 248 , 256 , 258 , 260 , 263 , 264 , 267 , 268 , 269 ,
B
122 , 123 , 126 , 130 , 164 , 165 , 166 , 167 , 220 , 221 , 222 , 223 , 224 , 234 , 235 , 238 , 244 , 245 , 246 , 247 , 248 , 250 , 256 , 258 , 260 , 263 , 264 , 267 , 268 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
79 , 80 , 81 , 82 , 120 , 121 , 125 , 166 , 189 , 191 , 192 , 193 , 194 , 195 , 212 , 213 , 214 , 215 , 216 , 217 , 218 , 219 , 226 , 227 , 230 , 231 ,
B
79 , 80 , 81 , 82 , 120 , 121 , 125 , 189 , 191 , 192 , 193 , 194 , 195 , 212 , 213 , 214 , 215 , 216 , 217 , 218 , 219 , 226 , 227 , 230 , 231 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation TYR(79)-, PHE(80)-, GLN(81)-, SER(82)-, No mutation
B No mutation No mutation TYR(79)-, PHE(80)-, GLN(81)-, SER(82)-, No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: