Pfam Domains mapped on to the structure: 2OTP

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF13895	Immunoglobulin domain	PF13895	PF13895
2	A	PF13895	Immunoglobulin domain	PF13895	PF13895

Conserved Domain Database Superfamily Annotations: 2OTP

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2OTP	212623	cl11960	Ig	superfamily - -
2	2OTP	212623	cl11960	Ig	superfamily - -

Structural Details of PDB entry 2OTP PDBid Chains Hinge Swapped Domain 2OTP A,B A:123-128,B:123-128 A:129-196,B:129-196 Swapped-domain interface residues and interactions: Chains Residues A 66, 69, 70, 92, 93, 94, 95, 96, 97, 98, 99, 100, 102, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 138, 142, 143, 144, 145, 146, 148, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 163, 164, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 181, 182, 183, 184, 185, 186, 187, 188, 190, 192, 193, 194, 195, 196, B 66, 69, 70, 90, 92, 93, 94, 95, 96, 97, 99, 100, 101, 102, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120, 121, 122, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136, 137, 138, 141, 142, 143, 144, 145, 152, 153, 154, 155, 156, 157, 158, 159, 160, 161, 162, 165, 166, 167, 168, 169, 170, 171, 172, 173, 174, 175, 176, 177, 179, 180, 181, 182, 183, 184, 185, 186, 187, 188, 190, 192, 193, 194, 195, Non-swapped-domain interface residues and interactions: Chains Residues A 9, 14, 15, 17, 71, 87, 90, 104, 106, 123, B 9, 14, 15, 17, 40, 71, 87, 89, 104, 106, 123,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	CYS(142)ARG,	No mutation	CYS(142)ARG,
B	No mutation	CYS(142)ARG,	No mutation	CYS(142)ARG,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2OTP

B:2OTP

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2OTP.ali
atm file:	2OTP.atm
cof file:	2OTP.cof
hbd file:	2OTP.hbd
html file:	2OTP.html
pdb file:	2OTP.pdb
ps file:	2OTP.ps
psa file:	2OTP.psa
rtf file:	2OTP.rtf
sst file:	2OTP.sst
tem file:	2OTP.tem