3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 2OKD

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF00692 dUTPase PF00692 PF00692

Conserved Domain Database Superfamily Annotations: 2OKD

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 2OKD 143638 cd07557 trimeric_dUTPase - cl00493

2 2OKD 207077 cl00493 trimeric_dUTPase superfamily - -

Structural Details of PDB entry 2OKD

Structural Details of PDB entry 2OKD

PDBid Chains Hinge Swapped Domain

2OKD A,B A:122-125,B:122-125 A:126-132,B:126-131

Swapped-domain interface residues and interactions:

Chains Residues
A 9, 10, 12, 13, 57, 126, 127, 128, 129, 130, 131, 132,

B 126, 127, 128, 129, 131,

C 9, 10, 11, 12, 13, 57,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 11, 14, 22, 24, 26, 27, 28, 29, 30, 32, 45, 46, 47, 49, 55, 56, 59, 62, 63, 65, 68, 70, 73, 74, 76, 78, 81, 82, 83, 85, 86, 87, 89, 95, 97, 99, 101, 114, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125,

B 9, 10, 11, 12, 13, 14, 22, 24, 26, 28, 29, 30, 32, 45, 46, 47, 49, 55, 56, 59, 62, 63, 65, 68, 70, 73, 74, 76, 78, 80, 81, 82, 83, 85, 86, 87, 89, 95, 99, 101, 114, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125,

C 7, 8, 14, 22, 24, 26, 28, 29, 30, 32, 45, 46, 47, 49, 55, 59, 62, 63, 65, 68, 69, 70, 73, 74, 76, 78, 80, 81, 82, 83, 85, 86, 87, 89, 95, 97, 99, 101, 114, 116, 117, 118, 119, 120, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation GLY(28)PHE, No mutation

B No mutation No mutation GLY(28)PHE, No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2OKD C:2OKD

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 2OKD.ali
atm file: 2OKD.atm
cof file: 2OKD.cof
hbd file: 2OKD.hbd
html file: 2OKD.html
pdb file: 2OKD.pdb
ps file: 2OKD.ps
psa file: 2OKD.psa
rtf file: 2OKD.rtf
sst file: 2OKD.sst
tem file: 2OKD.tem