Pfam Domains mapped on to the structure: 2OCT
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00031
Cystatin domain
PF00031
PF00031
Gene Ontology Annotations: 2OCT
No.
GO ID
GO Description
Linkout - AmiGO
1
GO:0004869
cysteine-type endopeptidase inhibitor activity
GO:0004869
Conserved Domain Database Superfamily Annotations: 2OCT
No.
PDB ID
PSSM ID
CDD Accession
Superfamily Short Name
Linkout - CDD
1
2OCT
28923
CY
C
cl09238
2
2OCT
209003
CY
superfamily
C -
Structural Details of PDB entry 2OCT
Structural Details of PDB entry 2OCT
PDBid Chains Hinge Swapped Domain
2OCT
A,B
A:46-51,B:46-51
A:2-45,B:4-45
Swapped-domain interface residues and interactions:
Chains Residues
A
6 , 9 , 16 , 19 , 20 , 22 , 23 , 26 , 27 , 30 , 31 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 95 ,
B
6 , 15 , 16 , 19 , 20 , 22 , 23 , 26 , 27 , 31 , 33 , 35 , 36 , 37 , 38 , 39 , 40 , 41 , 42 , 43 , 44 , 45 , 51 , 52 , 53 , 54 , 55 , 56 , 57 , 58 , 59 , 60 , 82 ,
Non-swapped-domain interface residues and interactions:
Chains Residues
A
46 , 47 , 48 , 49 , 50 , 65 , 67 , 69 , 78 , 80 , 82 , 85 , 87 , 94 , 97 , 98 ,
B
46 , 47 , 48 , 49 , 50 , 65 , 67 , 69 , 71 , 78 , 80 , 85 , 87 , 94 , 95 , 97 ,
Mutations in critical regions:
Chains
Hinge
Domain swapped interface Non-swapped interface Swapped Domain
A No mutation TYR(31)GLU, No mutation SER(3)CYS, TYR(31)GLU, B No mutation TYR(31)GLU, No mutation TYR(31)GLU,
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output:
