Pfam Domains mapped on to the structure: 2OBA

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF01242	6-pyruvoyl tetrahydropterin synthase	PF01242	PF01242

Conserved Domain Database Superfamily Annotations: 2OBA

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2OBA	212183	cl00263	TFold	superfamily - -

Structural Details of PDB entry 2OBA PDBid Chains Hinge Swapped Domain 2OBA A,D,C,B A:14-17,D:14-17,C:14-17,B:14-17;A:27-30,D:27-30,C:27-30,B:27-30 A:18-26,D:18-26,C:18-26,B:18-26 Swapped-domain interface residues and interactions: Chains Residues A 18, 22, 23, 24, 26, 68, 69, B 18, 22, 23, 24, 26, 46, C 18, 22, 23, 26, D 18, 22, 23, 26, 68, 69, 118, E 0, 68, 69, F 0, 46, 68, 69, Non-swapped-domain interface residues and interactions: Chains Residues A 1, 0, 2, 3, 4, 5, 6, 10, 11, 12, 15, 17, 27, 28, 29, 30, 31, 42, 45, 46, 47, 48, 51, 52, 53, 70, 79, 81, 82, 83, 84, 87, 106, 108, 109, 110, 111, 112, 113, 114, 115, 118, B 2, 1, 0, 2, 3, 4, 5, 6, 10, 11, 12, 15, 17, 27, 28, 29, 30, 31, 42, 45, 47, 48, 51, 52, 53, 67, 68, 69, 70, 79, 81, 82, 83, 84, 87, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 118, C 1, 0, 2, 3, 4, 5, 6, 10, 11, 12, 15, 17, 27, 28, 29, 30, 31, 42, 45, 46, 47, 48, 51, 52, 53, 67, 68, 69, 70, 79, 81, 82, 83, 84, 87, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 118, D 1, 0, 2, 3, 4, 5, 6, 10, 11, 12, 15, 17, 27, 28, 29, 30, 31, 42, 45, 46, 47, 48, 51, 52, 53, 67, 70, 79, 81, 82, 83, 84, 87, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, E 2, 1, 2, 3, 4, 5, 6, 10, 11, 12, 15, 17, 18, 22, 23, 24, 26, 27, 28, 29, 30, 31, 42, 44, 45, 46, 47, 48, 51, 52, 53, 70, 79, 81, 82, 83, 84, 87, 106, 108, 109, 110, 111, 112, 113, 114, 115, F 1, 2, 3, 4, 5, 6, 10, 11, 12, 15, 17, 18, 22, 23, 24, 26, 27, 28, 29, 30, 31, 42, 45, 47, 48, 51, 52, 53, 64, 67, 70, 79, 81, 82, 83, 84, 87, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 118,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2OBA

B:2OBA

C:2OBA

D:2OBA

E:2OBA

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2OBA.ali
atm file:	2OBA.atm
cof file:	2OBA.cof
hbd file:	2OBA.hbd
html file:	2OBA.html
pdb file:	2OBA.pdb
ps file:	2OBA.ps
psa file:	2OBA.psa
rtf file:	2OBA.rtf
sst file:	2OBA.sst
tem file:	2OBA.tem