Pfam Domains mapped on to the structure: 2NZ2
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00764
Arginosuccinate synthase
PF00764
PF00764
Conserved Domain Database Superfamily Annotations: 2NZ2
Structural Details of PDB entry 2NZ2
Structural Details of PDB entry 2NZ2
PDBid
Chains
Hinge
Swapped Domain
2NZ2
A,B
A:361-385,B:361-385
A:386-407,B:386-300
Swapped-domain interface residues and interactions:
Chains
Residues
A
386 , 388 , 389 , 391 , 392 , 393 , 395 , 396 , 398 , 399 , 400 , 402 , 403 , 407 ,
D
120 , 126 , 130 , 133 , 134 , 137 , 146 , 328 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
84 , 85 , 86 , 120 , 121 , 126 , 129 , 130 , 133 , 134 , 135 , 137 , 146 , 148 , 151 , 155 , 157 , 196 , 197 , 198 , 199 , 201 , 213 , 214 , 218 , 265 , 267 , 269 , 271 , 272 , 273 , 274 , 275 , 276 , 277 , 278 , 279 , 295 , 296 , 299 , 300 , 302 , 304 , 307 , 308 , 311 , 315 , 319 , 325 , 328 , 329 , 330 , 350 , 354 , 355 , 356 , 357 , 359 , 360 , 361 , 362 , 363 , 364 , 369 , 370 , 372 , 374 , 375 , 376 , 378 , 380 , 383 , 384 , 385 ,
D
84 , 85 , 86 , 121 , 129 , 135 , 148 , 151 , 155 , 157 , 196 , 197 , 198 , 199 , 201 , 213 , 214 , 218 , 265 , 267 , 269 , 271 , 272 , 273 , 274 , 275 , 276 , 277 , 278 , 279 , 295 , 296 , 299 , 300 , 302 , 304 , 307 , 308 , 311 , 315 , 319 , 325 , 329 , 330 , 350 , 354 , 355 , 356 , 357 , 359 , 360 , 361 , 362 , 363 , 364 , 369 , 370 , 372 , 374 , 375 , 376 , 378 , 380 , 383 , 384 , 385 , 386 , 388 , 389 , 391 , 392 , 393 , 395 , 396 , 398 , 399 , 400 , 402 , 403 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: