Pfam Domains mapped on to the structure: 2NYY

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF01742	Clostridial neurotoxin zinc protease	PF01742	PF01742
2	A	PF07952	Clostridium neurotoxin, Translocation domain	PF07952	PF07952
3	A	PF07953	Clostridium neurotoxin, N-terminal receptor binding	PF07953	PF07953
4	A	PF13385	Concanavalin A-like lectin/glucanases superfamily	PF13385	PF13385
5	A	PF07951	Clostridium neurotoxin, C-terminal receptor binding	PF07951	PF07951
6	C	PF13927	Immunoglobulin domain	PF13927	PF13927
7	C	PF13927	Immunoglobulin domain	PF13927	PF13927
8	D	PF13927	Immunoglobulin domain	PF13927	PF13927

Gene Ontology Annotations: 2NYY

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0005576	extracellular region	GO:0005576

Conserved Domain Database Superfamily Annotations: 2NYY

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2NYY	143182	cd04981	IgV_H -	cl11960
2	2NYY	212623	cl11960	Ig	superfamily - -
3	2NYY	143186	cd04985	IgC_CH1 -	cl11960
4	2NYY	212623	cl11960	Ig	superfamily - -
5	2NYY	212623	cl11960	Ig	superfamily - -

Structural Details of PDB entry 2NYY PDBid Chains Hinge Swapped Domain 2NYY D,C D:42-46,C:45-49 D:2-41,C:1-44 Swapped-domain interface residues and interactions: Chains Residues C 36, 38, 40, 42, D 35, 39, 104, Non-swapped-domain interface residues and interactions: Chains Residues C 47, 48, 50, 53, 54, 59, 91, 93, 95, 98, 99, 100, 102, 120, 121, 122, 123, 125, 127, 128, 133, 135, 137, 139, 141, 142, 164, 165, 166, 167, 168, 171, 178, 180, 182, 184, 216, D 44, 45, 47, 59, 62, 95, 99, 100, 102, 103, 105, 106, 108, 109, 127, 128, 129, 130, 132, 140, 141, 142, 146, 148, 169, 170, 171, 172, 174, 176, 184, 186, 188, 214,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

D:2NYY

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2NYY.ali
atm file:	2NYY.atm
cof file:	2NYY.cof
hbd file:	2NYY.hbd
html file:	2NYY.html
pdb file:	2NYY.pdb
ps file:	2NYY.ps
psa file:	2NYY.psa
rtf file:	2NYY.rtf
sst file:	2NYY.sst
tem file:	2NYY.tem