Pfam Domains mapped on to the structure: 2NTX

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF03759	PRONE (Plant-specific Rop nucleotide exchanger)	PF03759	PF03759

Gene Ontology Annotations: 2NTX

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0005089	Rho guanyl-nucleotide exchange factor activity	GO:0005089

Conserved Domain Database Superfamily Annotations: 2NTX

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2NTX	190740	cl04247	PRONE	superfamily - -

Structural Details of PDB entry 2NTX PDBid Chains Hinge Swapped Domain 2NTX A,B A:32-36,B:32-36 A:4-31,B:4-31 Swapped-domain interface residues and interactions: Chains Residues A 7, 10, 12, 15, 16, 18, 19, 21, 22, 23, 28, 29, 30, 31, 36, 78, 79, 82, 83, 84, 323, 324, 325, B 7, 15, 16, 18, 19, 20, 21, 22, 23, 28, 29, 30, 31, 36, 78, 79, 82, 83, 84, 323, 324, 325, Non-swapped-domain interface residues and interactions: Chains Residues A 40, 74, 107, 362, B 40, 74, 81, 107,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

B:2NTX

A:2NTX

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2NTX.ali
atm file:	2NTX.atm
cof file:	2NTX.cof
hbd file:	2NTX.hbd
html file:	2NTX.html
pdb file:	2NTX.pdb
ps file:	2NTX.ps
psa file:	2NTX.psa
rtf file:	2NTX.rtf
sst file:	2NTX.sst
tem file:	2NTX.tem