Pfam Domains mapped on to the structure: 2NSN

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00619	Caspase recruitment domain	PF00619	PF00619

Gene Ontology Annotations: 2NSN

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0005622	intracellular	GO:0005622

Conserved Domain Database Superfamily Annotations: 2NSN

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2NSN	176738	cd08324	CARD_NOD1_CARD4 -	cl14633
2	2NSN	209876	cl14633	DD_superfamily	superfamily - -

Structural Details of PDB entry 2NSN PDBid Chains Hinge Swapped Domain 2NSN A,B A:95-102,B:95-102 A:103-110,B:103-110 Swapped-domain interface residues and interactions: Chains Residues A 91, 103, 104, 107, 109, 110, B 91, 103, 104, 107, 109, Non-swapped-domain interface residues and interactions: Chains Residues A 22, 26, 29, 30, 33, 34, 35, 36, 38, 39, 42, 46, 87, 88, 90, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101, B 22, 26, 29, 30, 33, 34, 35, 36, 38, 39, 42, 46, 87, 88, 90, 92, 93, 94, 95, 96, 97, 98, 99, 100, 101,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2NSN

B:2NSN

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2NSN.ali
atm file:	2NSN.atm
cof file:	2NSN.cof
hbd file:	2NSN.hbd
html file:	2NSN.html
pdb file:	2NSN.pdb
ps file:	2NSN.ps
psa file:	2NSN.psa
rtf file:	2NSN.rtf
sst file:	2NSN.sst
tem file:	2NSN.tem