Pfam Domains mapped on to the structure: 2MCP

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	L	PF13927	Immunoglobulin domain	PF13927	PF13927

Conserved Domain Database Superfamily Annotations: 2MCP

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2MCP	143182	cd04981	IgV_H -	cl11960
2	2MCP	212623	cl11960	Ig	superfamily - -
3	2MCP	143186	cd04985	IgC_CH1 -	cl11960
4	2MCP	212623	cl11960	Ig	superfamily - -
5	2MCP	212623	cl11960	Ig	superfamily - -

Structural Details of PDB entry 2MCP PDBid Chains Hinge Swapped Domain 2MCP H,L H:42-46,L:47-51 H:1-41,L:1-46 Swapped-domain interface residues and interactions: Chains Residues H 33, 35, 39, 106, 107, 108, L 34, 36, 38, 40, 42, 44, Non-swapped-domain interface residues and interactions: Chains Residues H 44, 45, 47, 50, 61, 64, 97, 101, 103, 105, 109, 110, 112, 113, 114, 131, 132, 133, 134, 135, 136, 138, 139, 145, 149, 151, 173, 175, 176, 178, 180, 186, 188, 190, L 49, 50, 52, 55, 56, 93, 95, 97, 100, 101, 102, 104, 105, 106, 122, 123, 124, 125, 127, 129, 130, 133, 137, 139, 141, 143, 166, 168, 169, 170, 180, 182, 184, 186, 214, 215, 217, 220,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
H	No mutation	No mutation	No mutation	No mutation
L	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:2MCP

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2MCP.ali
atm file:	2MCP.atm
cof file:	2MCP.cof
hbd file:	2MCP.hbd
html file:	2MCP.html
pdb file:	2MCP.pdb
ps file:	2MCP.ps
psa file:	2MCP.psa
rtf file:	2MCP.rtf
sst file:	2MCP.sst
tem file:	2MCP.tem