3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 2JGS

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 A PF01382 Avidin family PF01382 PF01382

2 A PF01382 Avidin family PF01382 PF01382

Conserved Domain Database Superfamily Annotations: 2JGS

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 2JGS 201760 Avidin superfamily N -

2 2JGS 201760 Avidin superfamily C -

Structural Details of PDB entry 2JGS

Structural Details of PDB entry 2JGS

PDBid Chains Hinge Swapped Domain

2JGS A,D,C,B A:59-61,D:59-61,C:59-61,B:59-61;A:69-71,D:69-71,C:69-71,B:69-71 A:62-68,D:62-68,C:62-68,B:62-68

Swapped-domain interface residues and interactions:

Chains Residues
A 42, 62, 64, 67,

D 18, 42, 44, 62, 64, 67,

Non-swapped-domain interface residues and interactions:

Chains Residues
A 8, 9, 10, 12, 13, 14, 15, 17, 19, 21, 23, 25, 27, 29, 31, 32, 34, 36, 38, 39, 40, 50, 52, 54, 56, 58, 60, 61, 71, 73, 118, 120, 130,

D 8, 9, 10, 12, 13, 14, 15, 17, 21, 23, 25, 27, 29, 31, 32, 34, 36, 38, 39, 40, 45, 52, 54, 56, 58, 60, 61, 71, 73, 120,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

A No mutation No mutation No mutation No mutation

D No mutation No mutation No mutation No mutation

C No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

D No mutation No mutation No mutation No mutation

C No mutation No mutation No mutation No mutation

B No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2JGS B:2JGS C:2JGS D:2JGS

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 2JGS.ali
atm file: 2JGS.atm
cof file: 2JGS.cof
hbd file: 2JGS.hbd
html file: 2JGS.html
pdb file: 2JGS.pdb
ps file: 2JGS.ps
psa file: 2JGS.psa
rtf file: 2JGS.rtf
sst file: 2JGS.sst
tem file: 2JGS.tem