3DSwap | Knowledgebase of 3D Domain Swapping in Proteins

Pfam Domains mapped on to the structure: 2JB5

No. Chain ID Pfam ID Pfam Description Linkout - Pfam Linkout - CDD

1 H PF13927 Immunoglobulin domain PF13927 PF13927

2 L PF13927 Immunoglobulin domain PF13927 PF13927

3 L PF13927 Immunoglobulin domain PF13927 PF13927

4 L PF13895 Immunoglobulin domain PF13895 PF13895

5 L PF13895 Immunoglobulin domain PF13895 PF13895

6 L PF00047 Immunoglobulin domain PF00047 PF00047

Conserved Domain Database Superfamily Annotations: 2JB5

No. PDB ID PSSM ID CDD Accession Superfamily Short Name Linkout - CDD

1 2JB5 212623 cl11960 Ig superfamily - -

2 2JB5 212623 cl11960 Ig superfamily - -

3 2JB5 212623 cl11960 Ig superfamily - -

Structural Details of PDB entry 2JB5

Structural Details of PDB entry 2JB5

PDBid Chains Hinge Swapped Domain

2JB5 H,L H:106-108,L:98-100 H:3-105,L:3-97

Swapped-domain interface residues and interactions:

Chains Residues
H 35, 37, 39, 44, 45, 47, 50, 59, 61, 95, 99, 102, 103, 105, 106, 107, 108, 110,

L 3, 38, 40, 45, 46, 48, 51, 56, 57, 58, 89, 91, 93, 97, 98, 99, 100, 102, 104,

Non-swapped-domain interface residues and interactions:

Chains Residues
H 111, 129, 130, 131, 132, 136, 137, 144, 148, 150, 171, 173, 174, 175, 176, 177, 178, 179, 186, 188, 216,

L 103, 121, 122, 123, 124, 126, 128, 129, 132, 134, 136, 138, 140, 142, 165, 167, 170, 172, 178, 179, 180, 182, 184, 210, 211,

Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.

Mutations in critical regions:

Chains Hinge Domain swapped interface Non-swapped interface Swapped Domain

H No mutation No mutation No mutation No mutation

L No mutation No mutation No mutation No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:2JB5 L:2JB5

JOY Structural annotation for hinge hinge and swapped domain:

Hinge Swapped domain

JOY output:

ali file: 2JB5.ali
atm file: 2JB5.atm
cof file: 2JB5.cof
hbd file: 2JB5.hbd
html file: 2JB5.html
pdb file: 2JB5.pdb
ps file: 2JB5.ps
psa file: 2JB5.psa
rtf file: 2JB5.rtf
sst file: 2JB5.sst
tem file: 2JB5.tem