Pfam Domains mapped on to the structure: 2IUF
Conserved Domain Database Superfamily Annotations: 2IUF
Structural Details of PDB entry 2IUF
Structural Details of PDB entry 2IUF
PDBid
Chains
Hinge
Swapped Domain
2IUF
A,E
A:55-63,E:55-63
A:2-54,E:2-54
Swapped-domain interface residues and interactions:
Chains
Residues
A
26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 42 , 43 , 45 , 46 , 47 , 49 , 50 , 51 , 53 , 54 , 62 , 146 , 148 , 149 , 151 , 340 , 342 , 345 , 350 , 353 , 354 , 425 , 426 , 427 , 429 , 430 , 431 , 432 , 433 , 434 ,
E
26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 , 36 , 37 , 38 , 39 , 40 , 42 , 43 , 45 , 46 , 47 , 49 , 50 , 51 , 53 , 54 , 62 , 146 , 148 , 149 , 151 , 340 , 342 , 345 , 350 , 353 , 354 , 425 , 426 , 427 , 429 , 430 , 431 , 432 , 433 , 434 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
55 , 56 , 57 , 58 , 59 , 60 , 66 , 108 , 109 , 110 , 111 , 147 , 150 , 152 , 154 , 155 , 158 , 161 , 162 , 163 , 164 , 165 , 167 , 182 , 241 , 244 , 247 , 248 , 249 , 251 , 252 , 255 , 256 , 259 , 282 , 283 , 288 , 290 , 315 , 317 , 318 , 346 , 349 , 356 , 357 , 435 , 436 , 461 , 464 , 465 , 468 , 469 , 496 , 497 , 499 , 568 , 570 , 576 , 578 , 579 , 600 , 601 , 603 , 604 , 606 , 607 , 609 , 613 , 614 , 615 , 616 , 618 , 619 , 621 , 624 , 627 , 630 , 631 , 650 , 655 , 683 , 684 , 686 , 687 , 688 , 689 ,
E
55 , 56 , 57 , 58 , 59 , 60 , 66 , 108 , 109 , 110 , 111 , 147 , 150 , 152 , 154 , 155 , 158 , 160 , 161 , 162 , 163 , 164 , 165 , 167 , 182 , 241 , 244 , 247 , 248 , 249 , 251 , 252 , 255 , 256 , 259 , 282 , 283 , 288 , 290 , 315 , 317 , 318 , 346 , 349 , 356 , 357 , 435 , 436 , 461 , 464 , 465 , 468 , 469 , 496 , 497 , 499 , 568 , 570 , 576 , 578 , 579 , 600 , 601 , 603 , 604 , 606 , 607 , 609 , 613 , 614 , 615 , 616 , 618 , 619 , 621 , 624 , 627 , 630 , 631 , 650 , 655 , 683 , 684 , 686 , 687 , 688 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
E No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: