Pfam Domains mapped on to the structure: 2IFF

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	L	PF13895	Immunoglobulin domain	PF13895	PF13895
2	L	PF13927	Immunoglobulin domain	PF13927	PF13927
3	L	PF00047	Immunoglobulin domain	PF00047	PF00047
4	Y	PF00062	C-type lysozyme/alpha-lactalbumin family	PF00062	PF00062
5	Y	PF01464	Transglycosylase SLT domain	PF01464	PF01464

Conserved Domain Database Superfamily Annotations: 2IFF

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2IFF	212623	cl11960	Ig	superfamily - -
2	2IFF	143323	cd07699	IgC_L -	cl11960
3	2IFF	212623	cl11960	Ig	superfamily - -
4	2IFF	212623	cl11960	Ig	superfamily - -

Structural Details of PDB entry 2IFF PDBid Chains Hinge Swapped Domain 2IFF H,L H:42-44,L:40-42 H:2-41,L:1-39 Swapped-domain interface residues and interactions: Chains Residues H 35, 37, 39, L 35, 37, Non-swapped-domain interface residues and interactions: Chains Residues H 44, 45, 47, 61, 62, 95, 99, 100, 101, 104, 106, 107, 108, 125, 126, 127, 128, 129, 131, 133, 135, 136, 140, 144, 146, 167, 168, 169, 170, 172, 174, 179, 181, 183, 211, L 40, 41, 42, 43, 44, 45, 48, 49, 54, 55, 86, 90, 93, 94, 95, 96, 98, 112, 114, 116, 117, 119, 121, 122, 125, 129, 131, 133, 135, 136, 158, 159, 160, 161, 162, 165, 172, 174, 176, 178, 205, 212,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
H	No mutation	No mutation	No mutation	No mutation
L	No mutation	No mutation	ASN(93)HIS, -(95)TYR,	LYS(18)ARG, SER(26)ASN, ASN(30)SER, TYR(33)HIS,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:2IFF

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2IFF.ali
atm file:	2IFF.atm
cof file:	2IFF.cof
hbd file:	2IFF.hbd
html file:	2IFF.html
pdb file:	2IFF.pdb
ps file:	2IFF.ps
psa file:	2IFF.psa
rtf file:	2IFF.rtf
sst file:	2IFF.sst
tem file:	2IFF.tem