Pfam Domains mapped on to the structure: 2I8D

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF08818	Domain of unknown function (DU1801)	PF08818	PF08818

Conserved Domain Database Superfamily Annotations: 2I8D

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2I8D	210061	cl15265	DUF419	superfamily - -

Structural Details of PDB entry 2I8D PDBid Chains Hinge Swapped Domain 2I8D A,B A:86-88,B:86-88 A:89-121,B:89-121 Swapped-domain interface residues and interactions: Chains Residues A 16, 49, 50, 51, 52, 60, 61, 62, 63, 64, 65, 67, 70, 73, 83, 84, 85, 86, 89, 90, 91, 92, 93, 95, 96, 97, 98, 99, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 112, 113, 114, 116, 119, 120, 121, 122, B 16, 49, 50, 51, 52, 60, 61, 62, 63, 64, 65, 67, 70, 83, 84, 85, 86, 89, 90, 91, 92, 93, 95, 96, 97, 98, 99, 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 112, 113, 114, 116, 118, 119, 120, 121, Non-swapped-domain interface residues and interactions: Chains Residues A 19, 23, 26, 30, 31, 33, 34, 39, 40, 45, 46, 47, 48, 59, 66, 68, 69, 72, 74, 75, 78, 81, 87, 88, B 19, 23, 26, 30, 31, 33, 34, 39, 40, 45, 46, 47, 48, 66, 68, 69, 72, 73, 74, 75, 77, 78, 81, 82, 87, 88,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2I8D

B:2I8D

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2I8D.ali
atm file:	2I8D.atm
cof file:	2I8D.cof
hbd file:	2I8D.hbd
html file:	2I8D.html
pdb file:	2I8D.pdb
ps file:	2I8D.ps
psa file:	2I8D.psa
rtf file:	2I8D.rtf
sst file:	2I8D.sst
tem file:	2I8D.tem