Pfam Domains mapped on to the structure: 2I8B

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF11507	Ebola virus-specific transcription factor VP30	PF11507	PF11507

Conserved Domain Database Superfamily Annotations: 2I8B

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2I8B	151944	cl13024	Transcript_VP30	superfamily - -

Structural Details of PDB entry 2I8B PDBid Chains Hinge Swapped Domain 2I8B A,B A:248-251,B:248-251 A:252-266,B:252-266 Swapped-domain interface residues and interactions: Chains Residues A 140, 141, 142, 150, 169, 173, 252, 253, 255, 257, 258, 260, 261, 262, 263, 264, 265, 266, B 141, 142, 150, 153, 169, 173, 252, 253, 257, 258, 260, 261, 262, 263, 264, 265, Non-swapped-domain interface residues and interactions: Chains Residues A 143, 144, 145, 146, 147, 148, 149, 152, 153, 154, 166, 172, 176, 179, 180, 181, 185, 246, 247, 248, 249, 250, 251, B 139, 140, 143, 144, 145, 146, 147, 148, 149, 152, 154, 166, 172, 176, 180, 181, 185, 246, 247, 248, 249, 250, 251,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	GLY(140)-, ALA(141)-,	No mutation	No mutation
B	No mutation	ALA(141)-,	GLN(139)-, GLY(140)-,	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2I8B

B:2I8B

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2I8B.ali
atm file:	2I8B.atm
cof file:	2I8B.cof
hbd file:	2I8B.hbd
html file:	2I8B.html
pdb file:	2I8B.pdb
ps file:	2I8B.ps
psa file:	2I8B.psa
rtf file:	2I8B.rtf
sst file:	2I8B.sst
tem file:	2I8B.tem