Pfam Domains mapped on to the structure: 2I76
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF10728
Domain of unknown function (DUF2520)
PF10728
PF10728
Conserved Domain Database Superfamily Annotations: 2I76
Structural Details of PDB entry 2I76
Structural Details of PDB entry 2I76
PDBid
Chains
Hinge
Swapped Domain
2I76
A,B
A:206-209,B:206-209
A:210-257,B:210-257
Swapped-domain interface residues and interactions:
Chains
Residues
A
156 , 157 , 160 , 163 , 167 , 168 , 170 , 171 , 174 , 211 , 212 , 213 , 214 , 215 , 218 , 219 , 220 , 222 , 223 , 226 , 227 , 230 , 231 , 234 , 237 , 239 , 240 , 241 , 243 , 244 , 247 , 248 , 250 , 251 , 257 ,
B
65 , 66 , 67 , 108 , 109 , 156 , 157 , 160 , 163 , 167 , 168 , 170 , 171 , 212 , 213 , 214 , 215 , 223 , 226 , 227 , 230 , 231 , 234 , 239 , 240 , 241 , 243 , 244 , 247 , 248 , 250 , 251 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
89 , 106 , 107 , 121 , 123 , 148 , 150 , 154 , 158 , 159 , 161 , 162 , 164 , 165 , 166 , 169 , 172 , 173 , 175 , 176 , 177 , 179 , 180 , 182 , 183 , 185 , 189 , 190 , 191 , 192 , 193 , 194 , 195 , 197 , 198 , 199 , 200 , 201 , 202 , 203 , 204 , 205 , 207 , 208 , 209 ,
B
89 , 106 , 107 , 112 , 115 , 121 , 123 , 148 , 154 , 158 , 159 , 161 , 162 , 164 , 165 , 166 , 169 , 172 , 173 , 174 , 175 , 176 , 177 , 178 , 179 , 180 , 182 , 183 , 185 , 189 , 190 , 191 , 192 , 193 , 194 , 195 , 197 , 199 , 200 , 201 , 203 , 204 , 207 , 208 , 209 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: