Pfam Domains mapped on to the structure: 2HXI
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF00440
Bacterial regulatory proteins, tetR family
PF00440
PF00440
2
A
PF02909
Tetracyclin repressor, C-terminal all-alpha domain
PF02909
PF02909
Gene Ontology Annotations: 2HXI
No.
GO ID
GO Description
Linkout - AmiGO
1
GO:0045892
negative regulation of transcription, DNA-dependent
GO:0045892
Conserved Domain Database Superfamily Annotations: 2HXI
No.
PDB ID
PSSM ID
CDD Accession
Superfamily Short Name
Linkout - CDD
1
2HXI
212173
HTH
superfamily
N -
Structural Details of PDB entry 2HXI
Structural Details of PDB entry 2HXI
PDBid Chains Hinge Swapped Domain
2HXI
A,B
A:189-195,B:189-195
A:196-217,B:196-217
Swapped-domain interface residues and interactions:
Chains Residues
A
138 , 196 , 197 , 200 , 203 , 204 , 207 , 208 , 210 , 211 , 217 ,
B
138 , 196 , 197 , 200 , 203 , 204 , 207 , 208 , 210 , 211 ,
Non-swapped-domain interface residues and interactions:
Chains Residues
A
50 , 52 , 53 , 56 , 102 , 103 , 104 , 105 , 107 , 109 , 111 , 112 , 113 , 116 , 119 , 120 , 123 , 129 , 132 , 133 , 136 , 137 , 140 , 141 , 142 , 145 , 146 , 148 , 149 , 152 , 171 , 172 , 173 , 174 , 175 , 179 , 180 , 181 , 182 , 183 , 185 , 186 , 189 , 190 , 191 , 192 , 193 , 194 , 195 ,
B
102 , 103 , 104 , 105 , 106 , 107 , 109 , 111 , 112 , 113 , 116 , 119 , 120 , 123 , 129 , 132 , 133 , 136 , 137 , 140 , 141 , 142 , 144 , 145 , 146 , 148 , 149 , 152 , 167 , 168 , 169 , 171 , 174 , 175 , 179 , 180 , 181 , 182 , 183 , 185 , 186 , 189 , 190 , 191 , 193 , 194 , 195 ,
Mutations in critical regions:
Chains
Hinge
Domain swapped interface Non-swapped interface Swapped Domain
A No mutation No mutation No mutation No mutation B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output:
