Pfam Domains mapped on to the structure: 2HRM

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00692	dUTPase	PF00692	PF00692

Conserved Domain Database Superfamily Annotations: 2HRM

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2HRM	143638	cd07557	trimeric_dUTPase -	cl00493
2	2HRM	207077	cl00493	trimeric_dUTPase	superfamily - -

Structural Details of PDB entry 2HRM PDBid Chains Hinge Swapped Domain 2HRM A,B A:125-130,B:125-130 A:131-137,B:131-137 Swapped-domain interface residues and interactions: Chains Residues A 4, 5, 6, 8, 131, 132, 133, 134, 135, 136, 137, B 131, 132, 133, 134, 135, 136, 137, C 4, 5, 6, 8, Non-swapped-domain interface residues and interactions: Chains Residues A 1, 2, 3, 7, 9, 20, 21, 23, 25, 26, 27, 28, 29, 30, 31, 46, 48, 50, 57, 58, 62, 63, 64, 65, 69, 70, 72, 75, 76, 81, 83, 84, 85, 86, 88, 90, 91, 92, 94, 100, 102, 104, 106, 119, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, B 1, 2, 3, 4, 5, 6, 7, 8, 9, 20, 21, 23, 25, 26, 27, 28, 29, 30, 31, 46, 48, 50, 57, 58, 62, 63, 64, 65, 69, 70, 72, 75, 76, 81, 83, 84, 85, 86, 88, 90, 91, 92, 94, 100, 102, 104, 106, 119, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, C 1, 2, 3, 7, 9, 20, 21, 23, 25, 26, 27, 28, 29, 30, 31, 46, 48, 50, 57, 58, 62, 63, 64, 65, 69, 70, 72, 75, 76, 81, 83, 84, 85, 86, 88, 90, 91, 92, 94, 100, 102, 104, 106, 119, 121, 122, 123, 124, 125, 126, 127, 128, 129, 130, 131, 132, 133, 134, 135, 136,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2HRM

C:2HRM

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2HRM.ali
atm file:	2HRM.atm
cof file:	2HRM.cof
hbd file:	2HRM.hbd
html file:	2HRM.html
pdb file:	2HRM.pdb
ps file:	2HRM.ps
psa file:	2HRM.psa
rtf file:	2HRM.rtf
sst file:	2HRM.sst
tem file:	2HRM.tem