Pfam Domains mapped on to the structure: 2HQU

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00692	dUTPase	PF00692	PF00692

Conserved Domain Database Superfamily Annotations: 2HQU

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2HQU	143638	cd07557	trimeric_dUTPase -	cl00493
2	2HQU	207077	cl00493	trimeric_dUTPase	superfamily - -

Structural Details of PDB entry 2HQU PDBid Chains Hinge Swapped Domain 2HQU A,B A:139-144,B:139-144 A:145-164,B:145-164 Swapped-domain interface residues and interactions: Chains Residues A 27, 28, 29, 104, 105, 106, 107, 145, 146, 147, 148, 149, 151, 152, 153, 154, 155, 156, 157, 158, 159, 161, 162, 163, 164, B 41, 42, 86, 87, 126, 127, 128, 145, 146, 147, 148, 149, 151, 152, 153, 154, 155, 156, 157, 158, 159, 161, 162, 163, 164, C 27, 28, 29, 41, 42, 73, 86, 87, 104, 105, 106, 107, 126, 127, 128, Non-swapped-domain interface residues and interactions: Chains Residues A 24, 25, 26, 30, 38, 40, 44, 45, 46, 48, 61, 62, 63, 65, 71, 73, 75, 76, 77, 79, 81, 84, 86, 87, 89, 90, 91, 93, 95, 97, 98, 100, 102, 103, 110, 112, 114, 116, 131, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, B 24, 25, 26, 27, 28, 29, 30, 38, 40, 43, 44, 45, 46, 48, 61, 62, 63, 65, 75, 76, 79, 81, 84, 85, 89, 90, 91, 93, 95, 97, 98, 100, 102, 103, 104, 105, 110, 112, 114, 116, 118, 131, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, C 24, 25, 26, 30, 38, 40, 43, 44, 45, 46, 48, 61, 62, 63, 65, 71, 75, 76, 79, 81, 84, 85, 89, 90, 91, 93, 95, 97, 98, 100, 102, 103, 110, 112, 114, 116, 117, 131, 133, 134, 135, 136, 137, 138, 139, 140, 141, 142, 143, 144, 145, 146,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2HQU

C:2HQU

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2HQU.ali
atm file:	2HQU.atm
cof file:	2HQU.cof
hbd file:	2HQU.hbd
html file:	2HQU.html
pdb file:	2HQU.pdb
ps file:	2HQU.ps
psa file:	2HQU.psa
rtf file:	2HQU.rtf
sst file:	2HQU.sst
tem file:	2HQU.tem