Pfam Domains mapped on to the structure: 2HEZ

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF02275	Linear amide C-N hydrolases, choloylglycine hydrolase family	PF02275	PF02275

Gene Ontology Annotations: 2HEZ

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0016787	hydrolase activity	GO:0016787

Conserved Domain Database Superfamily Annotations: 2HEZ

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2HEZ	48435	cd00542	Ntn_PVA -	cl00467
2	2HEZ	212223	cl00467	Ntn_hydrolase	superfamily - -
3	2HEZ	212223	cl00467	Ntn_hydrolase	superfamily - -

Structural Details of PDB entry 2HEZ PDBid Chains Hinge Swapped Domain 2HEZ A,B A:191-194,B:191-194;A:206-209,B:206-209 A:195-205,B:195-205 Swapped-domain interface residues and interactions: Chains Residues Non-swapped-domain interface residues and interactions: Chains Residues A 85, 174, 178, 181, 182, 184, 185, 223, 316, B 85, 174, 178, 181, 182, 184, 185, 223, 224,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2HEZ

B:2HEZ

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2HEZ.ali
atm file:	2HEZ.atm
cof file:	2HEZ.cof
hbd file:	2HEZ.hbd
html file:	2HEZ.html
pdb file:	2HEZ.pdb
ps file:	2HEZ.ps
psa file:	2HEZ.psa
rtf file:	2HEZ.rtf
sst file:	2HEZ.sst
tem file:	2HEZ.tem