Pfam Domains mapped on to the structure: 2H6L

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF03479	Domain of unknown function (DUF296)	PF03479	PF03479

Conserved Domain Database Superfamily Annotations: 2H6L

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2H6L	211390	cd11378	DUF296 -	cl00720
2	2H6L	211441	cl00720	DUF296	superfamily - -

Structural Details of PDB entry 2H6L PDBid Chains Hinge Swapped Domain 2H6L A,D,C,B A:008-10,D:008-10,C:008-10,B:008-10 A:1-7,D:1-7,C:1-7,B:1-7 Swapped-domain interface residues and interactions: Chains Residues A 2, 3, 4, 5, 6, 7, 9, 10, 11, 12, 13, 14, 15, B 2, 3, 4, 5, 6, 7, 9, 10, 11, 12, 13, 14, 15, C 2, 3, 4, 5, 6, 7, 9, 10, 11, 12, 13, 14, 15, Non-swapped-domain interface residues and interactions: Chains Residues A 8, 18, 29, 33, 39, 41, 43, 44, 45, 47, 53, 54, 56, 57, 64, 69, 71, 73, 74, 76, 77, 78, 89, 91, 93, 96, 97, 98, 100, 101, 102, 103, 111, 112, 114, 116, 118, 120, 130, 132, 133, 135, 137, 138, 140, B 8, 18, 29, 33, 39, 41, 43, 44, 45, 47, 53, 54, 56, 57, 64, 69, 71, 73, 74, 76, 77, 78, 89, 91, 93, 96, 97, 98, 100, 101, 102, 103, 111, 112, 114, 116, 118, 120, 130, 132, 133, 135, 137, 138, 140, C 8, 18, 29, 33, 39, 41, 43, 44, 45, 47, 53, 54, 56, 57, 64, 69, 71, 73, 74, 76, 77, 78, 89, 91, 93, 96, 97, 98, 100, 101, 102, 103, 111, 112, 114, 116, 118, 120, 130, 132, 133, 135, 137, 138,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
D	No mutation	No mutation	No mutation	No mutation
C	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2H6L

B:2H6L

C:2H6L

D:2H6L

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2H6L.ali
atm file:	2H6L.atm
cof file:	2H6L.cof
hbd file:	2H6L.hbd
html file:	2H6L.html
pdb file:	2H6L.pdb
ps file:	2H6L.ps
psa file:	2H6L.psa
rtf file:	2H6L.rtf
sst file:	2H6L.sst
tem file:	2H6L.tem