Pfam Domains mapped on to the structure: 2H4P

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00079	Serpin (serine protease inhibitor)	PF00079	PF00079
2	B	PF00079	Serpin (serine protease inhibitor)	PF00079	PF00079

Conserved Domain Database Superfamily Annotations: 2H4P

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2H4P	206855	SERPIN	superfamily	N -

Structural Details of PDB entry 2H4P PDBid Chains Hinge Swapped Domain 2H4P A,B A:252-260,B:397-405 A:261-369,B:406-409 Swapped-domain interface residues and interactions: Chains Residues A 26, 27, 215, 221, 223, 261, 263, 264, 269, 271, 274, 275, 278, 280, 283, 287, 288, 295, 296, 297, 298, 299, 300, 301, 302, 304, 306, 360, 369, B 378, 379, 380, 381, 382, 383, 386, 406, 407, 408, Non-swapped-domain interface residues and interactions: Chains Residues A 5, 8, 9, 12, 16, 25, 28, 29, 30, 31, 32, 33, 101, 104, 105, 114, 193, 195, 212, 213, 214, 225, 229, 234, 236, 243, 245, 252, 253, 254, 255, 256, 257, 258, 259, 260, B 377, 384, 385, 387, 388, 389, 390, 391, 392, 393, 394, 396, 397, 398, 399, 400, 401, 402, 403, 404, 405,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2H4P

B:2H4P

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2H4P.ali
atm file:	2H4P.atm
cof file:	2H4P.cof
hbd file:	2H4P.hbd
html file:	2H4P.html
pdb file:	2H4P.pdb
ps file:	2H4P.ps
psa file:	2H4P.psa
rtf file:	2H4P.rtf
sst file:	2H4P.sst
tem file:	2H4P.tem