Pfam Domains mapped on to the structure: 2GPU

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00104	Ligand-binding domain of nuclear hormone receptor	PF00104	PF00104

Conserved Domain Database Superfamily Annotations: 2GPU

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2GPU	132744	cd06946	NR_LBD_ERR -	cl11397
2	2GPU	209301	cl11397	NR_LBD	superfamily - -

Structural Details of PDB entry 2GPU PDBid Chains Hinge Swapped Domain 2GPU A,B A:412-420,B:412-420 A:421-455,B:421-455 Swapped-domain interface residues and interactions: Chains Residues A 378, 421, 422, 423, 425, 426, 429, 433, 455, B 378, 421, 422, 423, 425, 426, 429, 433, Non-swapped-domain interface residues and interactions: Chains Residues A 351, 354, 355, 372, 376, 379, 385, 389, 392, 393, 396, 397, 400, 412, 415, 416, 418, 419, B 351, 354, 355, 372, 376, 379, 385, 389, 392, 393, 396, 397, 400, 412, 415, 416, 418, 419,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2GPU

B:2GPU

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2GPU.ali
atm file:	2GPU.atm
pdb file:	2GPU.pdb
psa file:	2GPU.psa
sst file:	2GPU.sst