Pfam Domains mapped on to the structure: 2GCY

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF13927	Immunoglobulin domain	PF13927	PF13927
2	A	PF13927	Immunoglobulin domain	PF13927	PF13927

Conserved Domain Database Superfamily Annotations: 2GCY

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2GCY	143182	cd04981	IgV_H -	cl11960
2	2GCY	212623	cl11960	Ig	superfamily - -
3	2GCY	143186	cd04985	IgC_CH1 -	cl11960
4	2GCY	212623	cl11960	Ig	superfamily - -
5	2GCY	212623	cl11960	Ig	superfamily - -

Structural Details of PDB entry 2GCY PDBid Chains Hinge Swapped Domain 2GCY A,B A:97-103,B:101-107 A:1-96,B:1-100 Swapped-domain interface residues and interactions: Chains Residues A 36, 38, 40, 42, 46, 47, 48, 50, 53, 54, 59, 91, 95, 100, 102, B 35, 37, 39, 44, 45, 47, 95, 99, 100, 103, 104, 105, 106, 108, 109, 110, Non-swapped-domain interface residues and interactions: Chains Residues A 99, 118, 120, 121, 122, 123, 125, 127, 128, 131, 133, 135, 137, 139, 141, 142, 164, 165, 166, 167, 168, 171, 178, 180, 182, 184, 211, 212, 213, 216, B 102, 127, 128, 129, 130, 132, 134, 135, 137, 142, 146, 148, 169, 171, 172, 174, 175, 176, 184, 186, 188, 214,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2GCY

B:2GCY

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2GCY.ali
atm file:	2GCY.atm
cof file:	2GCY.cof
hbd file:	2GCY.hbd
html file:	2GCY.html
pdb file:	2GCY.pdb
ps file:	2GCY.ps
psa file:	2GCY.psa
rtf file:	2GCY.rtf
sst file:	2GCY.sst
tem file:	2GCY.tem