Pfam Domains mapped on to the structure: 2GAN

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF13508	Acetyltransferase (GNAT) domain	PF13508	PF13508
2	A	PF00583	Acetyltransferase (GNAT) family	PF00583	PF00583
3	A	PF08445	FR47-like protein	PF08445	PF08445

Gene Ontology Annotations: 2GAN

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0016747	transferase activity, transferring acyl groups other than amino-acyl groups	GO:0016747

Conserved Domain Database Superfamily Annotations: 2GAN

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2GAN	173926	cd04301	NAT_SF -	cl00357
2	2GAN	212199	cl00357	NAT_SF	superfamily - -
3	2GAN	212199	cl00357	NAT_SF	superfamily - -

Structural Details of PDB entry 2GAN PDBid Chains Hinge Swapped Domain 2GAN A,B A:148-152,B:148-152 A:153-184,B:153-181 Swapped-domain interface residues and interactions: Chains Residues A 141, 142, 143, 144, 145, 146, 147, 148, 153, 154, 156, 157, 160, 162, 168, 170, 171, 172, 173, 174, 175, 176, 178, 181, 184, B 96, 142, 143, 144, 145, 146, 147, 148, 153, 156, 157, 160, 162, 165, 168, 169, 170, 171, 172, 173, 174, 175, 176, 178, Non-swapped-domain interface residues and interactions: Chains Residues A 32, 36, 95, 96, 98, 101, 112, 113, 124, 125, 128, 132, 136, 151, 152, B 32, 36, 95, 97, 98, 101, 112, 113, 124, 125, 128, 129, 132, 136, 141, 149, 151, 152,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	GLU(184)-,	No mutation	LEU(183)-, GLU(184)-,
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2GAN

B:2GAN

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2GAN.ali
atm file:	2GAN.atm
cof file:	2GAN.cof
hbd file:	2GAN.hbd
html file:	2GAN.html
pdb file:	2GAN.pdb
ps file:	2GAN.ps
psa file:	2GAN.psa
rtf file:	2GAN.rtf
sst file:	2GAN.sst
tem file:	2GAN.tem