Conserved Domain Database Superfamily Annotations: 2FRH

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2FRH	212173	cl00088	HTH	superfamily - -

Structural Details of PDB entry 2FRH PDBid Chains Hinge Swapped Domain 2FRH A,B A:107-111,B:107-111 A:98-105,B:98-105 Swapped-domain interface residues and interactions: Chains Residues A 100, 101, 103, 104, 105, 111, 115, B 100, 101, 103, 104, 105, 111, 115, Non-swapped-domain interface residues and interactions: Chains Residues A 106, 107, 108, 109, 110, 112, 113, 114, 116, 117, 118, 119, 120, 121, 122, 123, 134, 137, 138, 141, 145, 160, 161, 162, 208, 212, 215, 216, 219, 224, B 106, 107, 108, 109, 110, 112, 113, 114, 116, 117, 118, 119, 120, 121, 122, 123, 134, 137, 138, 141, 145, 160, 161, 162, 208, 212, 215, 216, 219, 223,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	HIS(100)-, MET(101)-,	No mutation	GLY(98)-, SER(99)-, HIS(100)-, MET(101)-,
B	No mutation	HIS(100)-, MET(101)-,	No mutation	GLY(98)-, SER(99)-, HIS(100)-, MET(101)-,

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2FRH

B:2FRH

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2FRH.ali
atm file:	2FRH.atm
cof file:	2FRH.cof
hbd file:	2FRH.hbd
html file:	2FRH.html
pdb file:	2FRH.pdb
ps file:	2FRH.ps
psa file:	2FRH.psa
rtf file:	2FRH.rtf
sst file:	2FRH.sst
tem file:	2FRH.tem