Pfam Domains mapped on to the structure: 2FML

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF00293	NUDIX domain	PF00293	PF00293

Conserved Domain Database Superfamily Annotations: 2FML

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2FML	212606	cl00447	Nudix_Hydrolase	superfamily - -
2	2FML	212606	cl00447	Nudix_Hydrolase	superfamily - -

Structural Details of PDB entry 2FML PDBid Chains Hinge Swapped Domain 2FML A,B A:33-38,B:33-38 A:3-32,B:4-32 Swapped-domain interface residues and interactions: Chains Residues A 15, 16, 18, 20, 23, 24, 27, 28, 64, 65, 66, 67, 120, B 15, 16, 18, 20, 23, 24, 27, 28, 64, 65, 66, 67, 120, Non-swapped-domain interface residues and interactions: Chains Residues A 35, 36, 37, 38, 39, 40, 69, 78, 79, 80, 81, 82, 83, 84, 85, 86, 108, 110, 111, 113, 115, 119, 121, 122, 124, 126, 141, 142, 200, 203, 268, B 35, 36, 37, 38, 39, 40, 69, 78, 79, 81, 82, 83, 84, 85, 86, 108, 110, 111, 113, 115, 119, 121, 122, 124, 126, 196, 203,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2FML

B:2FML

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2FML.ali
atm file:	2FML.atm
cof file:	2FML.cof
hbd file:	2FML.hbd
html file:	2FML.html
pdb file:	2FML.pdb
ps file:	2FML.ps
psa file:	2FML.psa
rtf file:	2FML.rtf
sst file:	2FML.sst
tem file:	2FML.tem