Pfam Domains mapped on to the structure: 2FE7
Conserved Domain Database Superfamily Annotations: 2FE7
Structural Details of PDB entry 2FE7
Structural Details of PDB entry 2FE7
PDBid
Chains
Hinge
Swapped Domain
2FE7
A,B
A:144-145,B:144-145
A:146-158,B:146-158
Swapped-domain interface residues and interactions:
Chains
Residues
A
103 , 106 , 107 , 115 , 116 , 117 , 118 , 119 , 120 , 136 , 137 , 138 , 139 , 140 , 146 , 147 , 148 , 149 , 152 , 153 , 154 , 156 , 157 , 158 ,
B
103 , 106 , 107 , 110 , 115 , 116 , 117 , 118 , 119 , 120 , 136 , 137 , 138 , 139 , 140 , 146 , 147 , 148 , 149 , 152 , 153 , 154 , 156 , 157 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
20 , 24 , 27 , 29 , 32 , 33 , 34 , 35 , 39 , 40 , 43 , 44 , 50 , 51 , 67 , 69 , 70 , 71 , 72 , 74 , 75 , 76 , 77 , 79 , 84 , 85 , 99 , 102 , 109 , 110 , 114 , 121 , 122 , 123 , 129 , 133 , 135 , 141 , 142 , 143 , 144 , 145 ,
B
20 , 24 , 27 , 29 , 32 , 33 , 34 , 35 , 39 , 40 , 43 , 44 , 50 , 51 , 67 , 69 , 70 , 71 , 72 , 74 , 75 , 76 , 77 , 79 , 84 , 85 , 102 , 109 , 114 , 121 , 122 , 123 , 129 , 135 , 141 , 142 , 143 , 144 , 145 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: