Pfam Domains mapped on to the structure: 2FAT

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	L	PF13895	Immunoglobulin domain	PF13895	PF13895
2	L	PF00047	Immunoglobulin domain	PF00047	PF00047
3	H	PF13895	Immunoglobulin domain	PF13895	PF13895

Conserved Domain Database Superfamily Annotations: 2FAT

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2FAT	143182	cd04981	IgV_H -	cl11960
2	2FAT	212623	cl11960	Ig	superfamily - -
3	2FAT	212623	cl11960	Ig	superfamily - -
4	2FAT	212623	cl11960	Ig	superfamily - -

Structural Details of PDB entry 2FAT PDBid Chains Hinge Swapped Domain 2FAT H,L H:42-46,L:41-45 H:1-41,L:1-40 Swapped-domain interface residues and interactions: Chains Residues H 39, L 34, 36, 38, Non-swapped-domain interface residues and interactions: Chains Residues H 44, 45, 47, 58, 60, 61, 91, 95, 98, 99, 100, 101, 103, 104, 105, 122, 123, 124, 125, 126, 132, 136, 138, 156, 159, 160, 161, 162, 164, 166, 171, 173, 175, 177, 203, L 43, 44, 46, 49, 50, 55, 56, 87, 89, 93, 94, 96, 98, 100, 113, 115, 117, 118, 119, 120, 122, 123, 126, 130, 132, 134, 136, 137, 159, 160, 161, 162, 163, 166, 168, 173, 175, 177, 179, 213,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
H	No mutation	No mutation	No mutation	No mutation
L	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:2FAT

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2FAT.ali
atm file:	2FAT.atm
cof file:	2FAT.cof
hbd file:	2FAT.hbd
html file:	2FAT.html
pdb file:	2FAT.pdb
ps file:	2FAT.ps
psa file:	2FAT.psa
rtf file:	2FAT.rtf
sst file:	2FAT.sst
tem file:	2FAT.tem