Pfam Domains mapped on to the structure: 2F2E
No.
Chain ID
Pfam ID
Pfam Description
Linkout - Pfam
Linkout - CDD
1
A
PF01638
HxlR-like helix-turn-helix
PF01638
PF01638
Conserved Domain Database Superfamily Annotations: 2F2E
Structural Details of PDB entry 2F2E
Structural Details of PDB entry 2F2E
PDBid
Chains
Hinge
Swapped Domain
2F2E
A,B
A:126-127,B:126-127
A:128-146,B:128-145
Swapped-domain interface residues and interactions:
Chains
Residues
A
90 , 91 , 112 , 113 , 114 , 115 , 116 , 117 , 123 , 124 , 128 , 129 , 130 , 131 , 136 , 138 , 139 , 140 , 141 , 142 , 143 , 144 , 145 , 146 ,
B
90 , 91 , 112 , 113 , 114 , 115 , 116 , 117 , 123 , 124 , 128 , 129 , 130 , 131 , 136 , 138 , 139 , 140 , 141 , 142 , 143 , 144 ,
Non-swapped-domain interface residues and interactions:
Chains
Residues
A
6 , 7 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 20 , 21 , 22 , 23 , 24 , 25 , 28 , 31 , 35 , 84 , 85 , 87 , 88 , 89 , 92 , 93 , 95 , 96 , 97 , 99 , 100 , 103 , 104 , 105 , 109 , 111 , 120 , 126 , 127 ,
B
7 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 20 , 21 , 22 , 23 , 24 , 25 , 28 , 31 , 35 , 84 , 85 , 87 , 88 , 89 , 92 , 93 , 94 , 95 , 96 , 97 , 99 , 100 , 103 , 104 , 105 , 109 , 111 , 120 , 126 , 127 ,
Swapped domains are represented using trasperent spheres.
Non-swapped part is represented using light color and cartoon representation.
Hinge region is shown in yellow color.
Mutations in critical regions:
Chains
Hinge
Domain swapped interface
Non-swapped interface
Swapped Domain
A No mutation No mutation No mutation No mutation
B No mutation No mutation No mutation No mutation
HIDE output:
JMOL Visualization:
2D-plot:
JOY Structural annotation for hinge hinge and swapped domain:
JOY output: