Pfam Domains mapped on to the structure: 2F1F

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	A	PF01842	ACT domain	PF01842	PF01842
2	A	PF13710	ACT domain	PF13710	PF13710
3	A	PF10369	Small subunit of acetolactate synthase	PF10369	PF10369

Gene Ontology Annotations: 2F1F

No.	GO ID	GO Description	Linkout - AmiGO
1	GO:0008152	metabolic process	GO:0008152

Conserved Domain Database Superfamily Annotations: 2F1F

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2F1F	153150	cd04878	ACT_AHAS -	cl09141
2	2F1F	208988	cl09141	ACT	superfamily - -
3	2F1F	204463	cl11035	ALS_ss_C	superfamily - -
4	2F1F	204463	cl11035	ALS_ss_C	superfamily - -

Structural Details of PDB entry 2F1F PDBid Chains Hinge Swapped Domain 2F1F A,B A:150-153,B:150-153 A:154-163,B:154-158 Swapped-domain interface residues and interactions: Chains Residues A 114, 148, 154, 155, 156, 157, 158, 159, 161, 162, 163, B 114, 116, 148, 154, 155, 156, 157, Non-swapped-domain interface residues and interactions: Chains Residues A 11, 13, 14, 16, 17, 20, 21, 24, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 45, 82, 84, 86, 88, 90, 109, 113, 116, 119, 121, 123, 125, 139, 146, 147, 149, 150, 151, 153, B 13, 14, 16, 17, 20, 21, 24, 27, 29, 30, 31, 32, 33, 34, 35, 36, 37, 39, 45, 82, 84, 86, 88, 90, 92, 111, 113, 119, 121, 123, 125, 135, 139, 144, 145, 146, 147, 149, 150, 153,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
A	No mutation	No mutation	No mutation	No mutation
B	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

A:2F1F

B:2F1F

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2F1F.ali
atm file:	2F1F.atm
cof file:	2F1F.cof
hbd file:	2F1F.hbd
html file:	2F1F.html
pdb file:	2F1F.pdb
ps file:	2F1F.ps
psa file:	2F1F.psa
rtf file:	2F1F.rtf
sst file:	2F1F.sst
tem file:	2F1F.tem