Pfam Domains mapped on to the structure: 2F19

No.	Chain ID	Pfam ID	Pfam Description	Linkout - Pfam	Linkout - CDD
1	L	PF13895	Immunoglobulin domain	PF13895	PF13895
2	H	PF13895	Immunoglobulin domain	PF13895	PF13895

Conserved Domain Database Superfamily Annotations: 2F19

No.	PDB ID	PSSM ID	CDD Accession	Superfamily Short Name	Linkout - CDD
1	2F19	143182	cd04981	IgV_H -	cl11960
2	2F19	212623	cl11960	Ig	superfamily - -
3	2F19	212623	cl11960	Ig	superfamily - -
4	2F19	212623	cl11960	Ig	superfamily - -

Structural Details of PDB entry 2F19 PDBid Chains Hinge Swapped Domain 2F19 H,L H:136-142,L:119-123 H:143-221,L:124-214 Swapped-domain interface residues and interactions: Chains Residues H 133, 138, 139, 140, 148, 152, 154, 175, 176, 177, 178, 180, 182, 189, 191, 219, L 116, 124, 127, 131, 133, 135, 137, 138, 160, 161, 162, 164, 174, 176, 178, 180, 207, 208, 209, 213, 214, Non-swapped-domain interface residues and interactions: Chains Residues H 39, 44, 45, 47, 59, 61, 95, 104, 105, 106, 107, 108, 109, 110, 111, 112, 114, 115, 116, 134, 135, 136, 137, 141, L 32, 34, 36, 38, 42, 43, 44, 45, 46, 49, 50, 55, 87, 89, 91, 92, 94, 95, 96, 98, 100, 114, 117, 118, 119, 121, 123,

Swapped domains are represented using trasperent spheres. Non-swapped part is represented using light color and cartoon representation. Hinge region is shown in yellow color.

Mutations in critical regions:

Chains	Hinge	Domain swapped interface	Non-swapped interface	Swapped Domain
H	No mutation	No mutation	No mutation	No mutation
L	No mutation	No mutation	No mutation	No mutation

HIDE output:

Homologues found through HIDE algorithm

JMOL Visualization:

2D-plot:

H:2F19

JOY Structural annotation for hinge hinge and swapped domain:

Hinge	Swapped domain

JOY output:

ali file:	2F19.ali
atm file:	2F19.atm
cof file:	2F19.cof
hbd file:	2F19.hbd
html file:	2F19.html
pdb file:	2F19.pdb
ps file:	2F19.ps
psa file:	2F19.psa
rtf file:	2F19.rtf
sst file:	2F19.sst
tem file:	2F19.tem